Matteo Fornai Selected Research

2,4-dinitrobenzenesulfonic acid

6/2021	Preclinical Development of FA5, a Novel AMP-Activated Protein Kinase (AMPK) Activator as an Innovative Drug for the Management of Bowel Inflammation.
1/2020	Deepening the Mechanisms of Visceral Pain Persistence: An Evaluation of the Gut-Spinal Cord Relationship.
11/2017	Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease.
2/2015	An integrated assessment of histopathological changes of the enteric neuromuscular compartment in experimental colitis.
1/2014	Involvement of the P2X7 purinergic receptor in colonic motor dysfunction associated with bowel inflammation in rats.
1/2011	Differential recruitment of high affinity A1 and A2A adenosine receptors in the control of colonic neuromuscular function in experimental colitis.
11/2010	The blockade of adenosine deaminase ameliorates chronic experimental colitis through the recruitment of adenosine A2A and A3 receptors.
3/2009	Exploiting the pyrazolo[3,4-d]pyrimidin-4-one ring system as a useful template to obtain potent adenosine deaminase inhibitors.
8/2007	Inhibition of adenosine deaminase attenuates inflammation in experimental colitis.
6/2006	Differential role of cyclooxygenase 1 and 2 isoforms in the modulation of colonic neuromuscular function in experimental inflammation.

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Matteo Fornai Research Topics

Disease

33	Inflammation (Inflammations) 08/2022 - 05/2003
14	Colitis 08/2022 - 05/2003
11	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 10/2022 - 04/2008
9	Obesity 10/2021 - 12/2017
6	Pain (Aches) 01/2020 - 01/2006
5	Alzheimer Disease (Alzheimer's Disease) 12/2021 - 01/2019
5	Neoplasms (Cancer) 01/2021 - 09/2014
4	Body Weight (Weight, Body) 08/2022 - 08/2007
3	Ischemia 01/2021 - 12/2008
3	Sepsis (Septicemia) 01/2019 - 06/2012
3	Ulcer 07/2012 - 03/2009
3	Stomach Ulcer (Gastric Ulcer) 07/2012 - 03/2009
3	Wounds and Injuries (Trauma) 06/2012 - 07/2005
2	Infections 05/2022 - 01/2019
2	Cognitive Dysfunction 12/2021 - 01/2021
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 01/2019
2	Atherosclerosis 01/2021 - 11/2020
2	Multiple Sclerosis 11/2020 - 06/2019
2	Rheumatoid Arthritis 11/2020 - 06/2012
2	Type 2 Diabetes Mellitus (MODY) 01/2020 - 06/2019
2	Hypersensitivity (Allergy) 01/2020 - 10/2017
2	Crohn Disease (Crohn's Disease) 01/2020 - 01/2020
2	Parkinson Disease (Parkinson's Disease) 06/2019 - 02/2016
2	Neuroinflammatory Diseases 06/2019 - 01/2019
2	Vomiting 10/2016 - 09/2010
2	Hemorrhage 02/2016 - 06/2009
2	Drug-Related Side Effects and Adverse Reactions 03/2014 - 10/2011
2	Peptic Ulcer (Peptic Ulcers) 02/2009 - 01/2008
1	Cardiomyopathies (Cardiomyopathy) 01/2021
1	Heart Failure 01/2021
1	Myocardial Infarction 01/2021
1	Hypertension (High Blood Pressure) 01/2021
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2021
1	Hypoxia (Hypoxemia) 07/2020
1	Carcinogenesis 07/2020
1	Insulin Resistance 01/2020
1	Morbid Obesity 01/2020

Drug/Important Bio-Agent (IBA)

14	Adenosine (Adenocard)FDA LinkGeneric 01/2021 - 02/2006
11	2,4-dinitrobenzenesulfonic acidIBA 06/2021 - 02/2006
9	InflammasomesIBA 08/2022 - 01/2017
9	2,4-dinitrofluorobenzene sulfonic acidIBA 08/2022 - 05/2003
9	Proteins (Proteins, Gene)FDA Link 01/2021 - 02/2016
8	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2018 - 07/2005
6	Pharmaceutical PreparationsIBA 06/2021 - 02/2006
6	CytokinesIBA 01/2020 - 08/2007
5	Dexamethasone (Maxidex)FDA LinkGeneric 06/2021 - 08/2007
5	NucleotidesIBA 01/2021 - 01/2017
5	Leucine (L-Leucine)FDA Link 01/2021 - 01/2017
5	Purinergic P1 Receptors (Adenosine Receptor)IBA 01/2020 - 04/2008
4	Cholinergic Agents (Cholinergics)IBA 02/2016 - 05/2003
3	Infliximab (Remicade)FDA Link 10/2022 - 01/2020
3	Oncostatin MIBA 10/2022 - 01/2020
3	Biomarkers (Surrogate Marker)IBA 10/2022 - 12/2019
3	EnzymesIBA 01/2021 - 04/2008
3	Purinergic Receptors (Receptors, Purine)IBA 01/2019 - 04/2008
3	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 10/2013 - 03/2005
3	Protein Isoforms (Isoforms)IBA 07/2012 - 01/2006
3	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 07/2012 - 01/2006
3	Adenosine DeaminaseIBA 06/2012 - 08/2007
3	AcidsIBA 01/2011 - 05/2003
2	vedolizumabIBA 10/2022 - 01/2020
2	2,4-dinitrobenzeneIBA 08/2022 - 01/2020
2	Purinergic P2X4 ReceptorsIBA 08/2022 - 01/2019
2	Sulfonic AcidsIBA 08/2022 - 01/2020
2	CholesterolIBA 10/2021 - 03/2014
2	Adenosine Triphosphate (ATP)IBA 01/2021 - 12/2008
2	LipidsIBA 01/2021 - 02/2016
2	InterleukinsIBA 01/2020 - 01/2019
2	CollagenIBA 01/2020 - 02/2015
2	FlavonoidsIBA 12/2018 - 01/2018
2	AntioxidantsIBA 12/2018 - 01/2018
2	Diclofenac (SR 38)FDA LinkGeneric 01/2018 - 07/2005
2	Monoclonal AntibodiesIBA 11/2017 - 01/2010
2	Malondialdehyde (Propanedial)IBA 02/2016 - 03/2009
2	Indomethacin (Indometacin)FDA LinkGeneric 07/2012 - 03/2009
2	Acetic Acid (Vinegar)FDA LinkGeneric 07/2012 - 03/2009
2	Caspase 3 (Caspase-3)IBA 07/2012 - 03/2009
2	SC 560IBA 07/2012 - 06/2006
2	Proliferating Cell Nuclear Antigen (PCNA)IBA 07/2012 - 03/2009
2	VaccinesIBA 01/2012 - 04/2011
2	Proton Pump InhibitorsIBA 01/2011 - 03/2009
2	9-(2-hydroxy-3-nonyl)adenine (EHNA)IBA 11/2010 - 08/2007
2	pyrazoleIBA 11/2010 - 08/2007
2	pyrimidineIBA 11/2010 - 08/2007
2	Paroxetine (Paxil)FDA LinkGeneric 07/2010 - 06/2009
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 06/2006 - 03/2005
1	OccludinIBA 08/2022
1	NP-1815-PXIBA 08/2022
1	Donepezil (Aricept)FDA LinkGeneric 12/2021
1	Substance PIBA 10/2021
1	AMP-Activated Protein KinasesIBA 06/2021
1	acadesineIBA 06/2021
1	NucleosidesIBA 01/2021
1	palmidrolIBA 01/2021
1	Immunomodulating AgentsIBA 11/2020
1	Leukocyte L1 Antigen Complex (Calgranulin)IBA 01/2020
1	Adenosine A3 ReceptorIBA 01/2020

Therapy/Procedure

4	Therapeutics 05/2022 - 11/2017
2	Drug Therapy (Chemotherapy) 11/2017 - 04/2008
1	Bariatric Surgery 01/2020